Publications by Current and Former IMSD Scholars

Adediran, S., Day, T., Sil, D., Kimbrell, M., Warshakoon, H., Malladi, S. & David, S. (2009, September/October). Synthesis of a Highly Water-Soluble Derivative of Amphotericin B with Attenuated Proinflammatory Activity. Molecular Pharmaceutics, 6(5), 1582-90.

Blackinton, J., Lakshminarasimhan, M., Thomas, K.J., Ahmad, R., Greggio, E., Raza, A.S., Cookson, M.R. & Wilson, M.A. (2009, March). Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. J Biol Chem, 284(10), 6476-85.

Ciaccio, N.A., Moreno, M.L., Bauer, R. & Laurence, J.S. (2008). High-Yield Expression in E. coli and Refolding of the bZIP Domain of Activating Transcription Factor 5. Protein Expression & Purification.

Day, T.P., Sil, D., Shukla, N.M., Anbanandam, A., Day, V.W. & David, S. (2010, December). Imbuing Aqueous Solubility to Amphotericin B and Nystatin with a Vitamin. Mol. Pharmaceutics.

Fischer, D.J., Walter R.V. I., Grigsby, R.J. & Lunte, S.M. (2005). Pyrolyzed Photoresist Carbon Electrodes for Microchip Electrophoresis with Dual-Electrode Amperometric Detection. Electroanalysis, 17(13), 1153-1159.

Greggio, E., Jain, S., Kingsbury, A., Bandopadhyay, R., Lewis, P., Kaganovich, A., van der Brug, M.P., Beilina, A., Blackinton, J., Thomas, K.J., Ahmad, R., Miller, D.W., Kesavapany, S., Singleton, A., Lees, A., Harvey, R.J., Harvey, K., & Cookson, M.R. (2006, August). Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol Dis, 23(2), 329-41.

Greggio, E., Zambrano, I., Kaganovich, A., Beilina, A., Taymans, J.M., Daniëls, V., Lewis, P., Jain, S., Ding, J., Syed, A.,Thomas, K.J., Baekelandt, V., Cookson, M.R. (2008, June). The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. J Biol Chem, 283(24), 16906-14.

Haque, M.E., Thomas, K.J., D'Souza, C., Callaghan, S., Kitada, T., Slack, R.S., Fraser, P., Cookson, M.R., Tandon, A., & Park, D.S. (2008, Feburary). Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci, 105(5), 1716-21.

Harris B.R., Yorks D.T., Bohnert C.A., Parmerlee J.S., & Powell R. (2004). Population densities and structural habitats of Anolis lizards in lowland habitats on Grenada. Caribbean Journal of Science, 40(1), 31-40.

Jones, L. S., Yazzie, B. & Middaugh, C.R. Polyanions and the Proteome. (3.8:  746-469, 2004). Molecular & Cellular Proteomics.

Markham A.P., Jaafar Z.A., Kemege K.E., Middaugh C.R.& Hefty P.S. (2009, November). Biophysical characterization of Chlamydia trachomatis CT584 supports its potential role as a type III secretion needle tip protein. Biochemistry, 48(43), 10353-61.

Mortiboys, H., Thomas. K.J., Koopman, W.J., Klaffke, S., Abou-Sleiman, P., Olpin, S., Wood, N.W., Willems, P.H., Smeitink, J.A., Cookson, M.R. & Bandmann, O. (2008, November). Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Ann Neurol, 64(5), 555-65.

Peek, L.J., Martin, T.T.,  Nation, C.E., Pegram, S.E. & Middaugh, C.R. (2006). Effects of Stabilizers on the Destabilization of Proteins upon Adssorption to Aluminum Salt AdjuvantsJournal of Pharmaceutical Sciences.

Rexroad, J., Martin, T.T., McNeilly, D., Godwin, S., & Middaugh, C.R. (2006). Thermal Stability of Adnovirus Type 2 as a Function of pH. Journal of Pharmaceutical Sciences, 95, 1469-1479.

Robinson, C.C., Willis, M., Meagher, A., Gieseker, K.E., Robart, H., & Glode, M.P. (2002, April). Impact of rapid polymerase chain reaction results on management of pediatric patients with enteroviral meningitis. Pediatric Infectious Disease Journal.

Sandebring, A., Thomas, K.J., Beilina, A., van der Brug, M., Cleland, M.M., Ahmad, R., Miller, D.W., Zambrano, I., Cowburn, R.F., Behbahani, H., Cedazo-Mínguez, A. & Cookson, M.R. (2009, May).Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. 
PLoS One, 27, 4(5), e5701.

Stensrud, K.F., Adam, P.R., LaMar, C.D., Olive, A.J., Lushington, G.H., Sudharsan, R., Shelton, N.L., Givens, R.S., Picking, W.L., & Picking, W.D. (2008). Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip. Journal of Biological Chemistry.

Thomas, K.J., McCoy, M.K., Blackinton, J., Beilina, A., van der Brug, M., Sandebring, A., Miller, D., Maric, D., Cedazo-Minguez, A., & Cookson, M.R. (2011, January). DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. 
Hum Mol Genet, 20(1), 40-50.

Thomas, K.J. & Cookson, M.R. (2009, October). The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics. Int J Biochem Cell Biol, 41(10), 2025-35.

van der Brug, M.P., Blackinton, J., Chandran, J., Hao, L.Y., Lal, A., Mazan-Mamczarz, K., Martindale, J., Xie, C., Ahmad R., Thomas, K.J., Beilina, A., Gibbs, J.R., Ding, J., Myers, A.J., Zhan, M., Cai, H., Bonini, N.M., Gorospe, M. & Cookson, M.R. (2008, July). RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci, 105(29), 10244-9.

Wacker, M.J., Best, S.R., Kosloski, L.M., Stachura, C.J., Smoot, R.L., Porter, C.B. & Orr, J.A. (2006, April). Thromboxane A2 induced arrhythmias in the anesthetized rabbit.  American Journal of Physiology: Heart and Circulatory Physiology.

Wacker, M.J., Wilhelm, H.L., Gomez, S.E., Floor, E., & Orr, J.A. (2003). The role of serotonin in the thromboxane A2 - induced coronary chemoreflex.American Journal of Physiology: Heart and Circulatory. Physiology, 284,   H867-H875,

Weihofen, A., Thomas, K.J., Ostaszewski, B.L., Cookson, M.R. & Selkoe, D.J. (2009, March). Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry, 48(9), 2045-52.

Williamson, K.E., Poche, Jr., A.J., Green, B.T., Harris, B.R., Germano, J.M., Simmons, P.M. Yorks, D.T., Powell, R., Parmerlee, Jr., J.S. & Henderson, R.W. (2003). Herpetofauna of Hog Island, Grenada. Herpetological Bulletin.

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